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Figure 1 presents estimates of survival probabilities of up to 5 years for patients with breast cancer by stage at diagnosis <a href=http://doxycycline.world/>doxycycline long-term side effects</a> Clearly, in either of these potential scenarios it would be expected that SERDs would be an effective therapeutic strategy, and indeed fulvestrant was recently shown to have clinical benefit in Her2 overexpressing cancers in patients who had failed endocrine therapy 75